The Mona Lisa Molecule Answers
Dear Diary: Today I have been witness to a most singular event. The day for me started off fairly uneventfully at the Cavendish Laboratory where I work as a laboratory assistant. As I recall, there was quite a nip in the winter air and as I watched. Draw the mirror image form of each molecule shown and use it to determine if the molecule is chiral in three dimensions. Be sure that you can explain your answers. For simplicity, assume that all of the bond angles in each structure are the same (about 109.5°) and that all of the bond lengths are identical. H H H H F H H H F Br H H F Br I H. NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE “Th e Mona Lisa Molecule” by Karobi Moitra Page 2 Questions 3. Why was it important to solve the structure of DNA?
Author(s)
Department of Biology
Trinity Washington University
MoitraK@trinitydc.edu
Abstract
This case study details the historical discovery of the structure of DNA. Images of this key molecule are as iconic as those of the Mona Lisa, and identifying its structure has proven to be as intriguing a mystery for scientists as the reason behind Mona Lisa's smile has been for art historians. The case is woven together by a series of fictional diary entries that detail the history of the discovery of DNA's structure, the major players involved, their ethical dilemmas, and the role of women in science. The case is designed for a high school course or introductory undergraduate genetics/ biochemistry courses. It can also be used as an interdisciplinary case study bridging genetics, bioethics, art, and the status of women in science. Designed as an interrupted case, it may be used in its entirety or in parts that pertain to a particular topic or discipline. No prior knowledge of genetics is required.
Objectives
- Accurately describe the chronology of events leading up to the discovery of DNA structure.
- Describe the key features of DNA and how these features explain experimental data such as Chargaff's rules and Rosalind Franklin's X-ray crystallographic results.
- Develop the skills to read and interpret scientific concepts from a primary research article.
- Learn how to independently gather information from websites and apply that information to problem solving and critical thinking.
- Explore the role of DNA in science, society, art, and literature.
- Become aware of the ethical issues involved in scientific research.
- Explore the role of women in science.
Keywords
DNA; deoxyribonucleic acid; x-ray crystallography; model building; double helix; Rosalind Franklin; Francis Crick; James Watson; Cavendish; Hershey-Chase; Chargraff’s Laws; photo 51
Topical Areas
Ethics, History of science, Science and the media, Women in scienceEducational Level
The Mona Lisa Molecule Answers
High school, Undergraduate lower divisionFormat
PDFType / Methods
Analysis (Issues), Dilemma/Decision, Discussion, Interrupted, Journal ArticleLanguage
EnglishSubject Headings
Biology (General) | Genetics / Heredity | Biochemistry | Molecular Biology |Date Posted
12/29/2014
Teaching Notes
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Answer Key
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Videos
The following video(s) are recommended for use in association with this case study.
- The Double Helix
Short film that tells the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Running time: 16:53 min. Produced by HHMI BioInteractive. ec) - The Chemical Structure of DNA
Short animation showing the detailed structure of DNA. Running time: 2:44 mins. Produced by HHMI BioInteractive. - Chargaff's Ratio
Short animation that discusses Erwin Chargaff’s 1950 publication stating that in the DNA of any given species, the ratio of adenine to thymine is equal, as is the ratio of cytosine to guanine. This became known as Chargaff's ratio, and it was an important clue for solving the structure of DNA. Running time: 0;49 min. Produced by HHMI BioInteractive.
The Mona Lisa Molecule Answers Answer
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Title: - The Mona Lisa Molecule Answers Edition Ebook
File Type: PDF EPUB MOBI.
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